One Hundred
Years Ago,
Cannabis was
KNOWN to be
a powerful healing
medicine.
Now,
even more is KNOWN...
even more is KNOWN...
(1) The Most Promising Cannabinoids So Far...
THC versus THCa
Most studies with cannabidiol utilize synthetic, single-molecule CBD produced by biochemical laboratories for research purposes. In contrast, whole plant extractions typically include more than 400 trace compounds. Many of these compounds interact synergistically to create what scientists refer to as an “entourage effect” that magnifies the therapeutic benefits of the plant’s individual components—so that the medicinal impact of the whole plant is greater than the sum of its parts.
It is important to consider the entourage effect when purchasing a hemp oil product: 100 milligrams of synthetic single-molecule CBD is not equivalent to 100 milligrams of a CBD-rich whole plant cannabis extract.
This is more than just CBD. This is a full spectrum, phytocannabinoid and terpene rich hemp oil.
This is more than just CBD. This is a full spectrum, phytocannabinoid and terpene rich hemp oil.
- Dozens of bio-active compounds naturally found in hemp oil
- Made from organically grown hemp plants in Colorado
- Full spectrum - extracted from the entire plant
- Zero THC
- Legal to purchase, use, and transport throughout the United States
Full spectrum hemp oil is naturally rich in cannabinoids and terpenes. Together, these unique compounds work synergistically to produce the sought after “entourage effect.”
(2) Dr. Sanjay Gupta CBD News Report
Did you know that the U.S. federal government holds the following patent?
“Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism. This new-found property makes cannabinoids useful in the treatment and prophylaxis of wide variety of oxidation associated diseases, such as ischemic, age-related, inflammatory and autoimmune diseases.
The cannabinoids are found to have particular application as neuroprotectants, for example in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease and HIV dementia."
The cannabinoids are found to have particular application as neuroprotectants, for example in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease and HIV dementia."
Endocannabinoids are made naturally by the human body.
Anandamide and arachidonoyl glycerol are compounds that are made by the human body.
Phytocannabinoids occur naturally in hemp.
(3) A Review of Cannabinoids and Terpenes
Although the cannabinoids found in hemp are NOT the same as those made by the human body, they are still able to have a positive impact on human health.
The Benefits of CBD:
People suffering from various health issues have found benefit for:
• Chronic pain and inflammation
• Arthritis
• Sleep disorders and insomnia
• Anxiety, stress, and depression
• Skin conditions
• Low appetite and poor metabolic function
• Weaker immune system
• Chronic diseases and cancer
Pain
CBD oil due to its analgesic properties is commonly recommended for chronic pain of all kinds, ranging from back pain to the full-body agony of cancer. It can disrupt the activity of pain receptors in the body and instead cause a release of neurotransmitters such as serotonin and dopamine – “feel good” compounds that can ease discomfort and pain, even if the pharmaceutical painkillers have no effect.
Nausea
CBD oil can cure vomiting and nausea. The non-psychotropic components of this oil activate certain autoreceptors, which causes antiemetic/anti-nausea effects in the body.
Inflammation
When it comes to inflammation, some people can only find relief with CBD oil, particularly those with advanced cases of rheumatoid arthritis, multiple sclerosis, migraines, joint disorders, and pervasive muscle pain. In some cases, people have reported nearly miraculous improvement in the inflammatory symptoms of chronic diseases.
Anxiety
CBD hemp oil is well known to reduce feelings of anxiety and stress, as well as prevent depressive episodes by increasing the levels of “positive” hormones and neurotransmitters in the body. Although some people claim that marijuana makes them “paranoid” or anxious, that is largely due to the psychotropic THC found in cannabis.
Alzheimer’s Disease
A number of studies have connected the use of cannabidiol (CBD) with decreased occurrence and severity of neurodegenerative diseases, such as Alzheimer’s and Huntington’s disease. This presents yet another exciting development for medical researchers, given the persistent challenges to finding effective solutions for these conditions.
Epilepsy
Highly concentrated doses of CBD oil have been successfully used to treat epilepsy in a number of research studies. While there has been quite a limited success in medication to prevent or treat epilepsy, the physical and neurological regulatory properties of CBD oil represent an exciting new solution for people with this seizure-inducing condition.
Cancer
Another major reason why CBD oil has been positively received in some parts of the medical community is its apparent effect on cancer and tumor growth. In multiple studies, the use of CBD oil (even direct injection into tumors) has resulted in tumor reduction or elimination. The antioxidants in CBD hemp oil also provide anti-mutagenic properties and lower users’ risk of cancer.
Anti-psychotic
Studies performed on animals and humans have found that CBD oil has anti-psychotic properties too. The research supports the idea that this oil could be a possible therapeutic option in treating psychosis such as schizophrenia.
Sleep
There is a strong sedative quality to CBD hemp oil, making it a popular remedy for people with insomnia, sleeplessness, interrupted sleep, post-traumatic stress disorder, restless leg disorder, and other night-time issues. Inhaling a small amount of CBD oil, applying it to your chest, or even putting a few drops on your pillow can help you get the good night’s sleep you’ve been seeking.
Immune System
The majority of cannabinoids have been proven to have positive effects on the body’s immune system, particularly CBD oil, as it can help regulate overactive immune systems. This means less susceptibility to allergens, and a possible application for autoimmune diseases, which are some of the most difficult-to-treat medical conditions.
Appetite
CBD oil is also known to control the appetite. This is largely due to the release of certain hormones in the body that control hunger and satiety. By optimizing the levels of these hormones based on the actual needs of your body, you can establish a healthy appetite, particularly following surgery, extended illness or injury.
Skin Care
Improving the appearance of the skin, especially reducing the signs and symptoms of acne and eczema, are the great benefits of regular CBD oil use. Topical application is quite popular for this, whether in a diluted or undiluted form, depending on the severity of the skin affliction. The powerful anti-inflammatory properties of the oil can also soothe redness, itchiness, and swollen areas of the skin.
Diabetes
Studies show that cannabidiol present in CBD oil can control diabetes and lower the level of insulin. Although a lot more research needs to be done in this area of study, initial studies have laid the foundation for the use of CBD oil to lower the risk of diabetics.
Promotes Heart Health
CBD oil is highly beneficial for the cardiovascular system too. It enhances the vasorelaxation of the arteries, protecting it against the vascular damage caused by inflammation in a high glucose environment. However, deeper studies need to be made in order to fully explore its dosage and effects on cardiovascular health.
Reduces Drug Relapses
The non-psychoactive constituent of Cannabis sativa, cannabidiol, has therapeutic uses in treating psychiatric disorders. It is used to fight alcoholism and cocaine addiction, which means it reduces alcohol and drug relapses.
Dosage
An appropriate dosage of CBD oil will depend on the individual, as well as the severity of the health condition a person is trying to remedy.
Chronic pain – 5 mg per day until the pain subsides.
Multiple sclerosis – Patients may take 80 mg per day for 2-3 weeks at a time to soothe their symptoms.
Medicinal applications – The average amount for most medicinal applications is 25 mg, taken twice per day.
If this is not sufficient for calming your symptoms, a gradual increase of another 25 mg per day, over the course of 3-4 weeks, is recommended. While there have been no reports of more serious side effects when this oil is taken in larger concentrations, it is best to slowly increase your dose to find a comfortable and effective level, given your individual characteristics and needs. [20]
Is CBD Oil Legal?
CBD oil is not legal everywhere. It is banned/restricted by countries such as UAE, Dubai, and Saudi Arabia. Although CBD oil is illegal in many of the US states too, some have legalized its use for medicinal purposes. While the number would be ever-changing, as of 2016 there are 17 states in the US which have legalized the use of low THC, high CBD products for medical reasons in limited situations. These states include Alabama, Georgia, Iowa, Kentucky, Florida, Mississippi, Louisiana, Missouri, North Carolina, Oklahoma, South Carolina, Wisconsin, Wyoming, Tennessee, Texas, Utah, and Virginia. It is advisable to consult your local health specialist before use.
Side Effects of CBD Oil
There are a number of possible side effects to using CBD oil, such as fatigue, dry mouth, lightheadedness, hypotension, and impaired motor functions. However, when used in moderate amounts, most people do not experience these side effects, and none of them are known for being fatal or particularly dangerous. [22] More than 20,000 studies have been done in the past 15 years on cannabis, hemp, and cannabinoids, and the results have been overwhelmingly supportive of the therapeutic potential and viability of CBD oil. That being said, some people should be cautious before using this powerful oil.
Blood Pressure – One of the notable soothing benefits of CBD oil is its effect on blood pressure, helping protect heart health and promote calmness in the body. However, if you are already taking medication for hypertension, combining this with CBD oil can potentially cause dangerously low blood pressure (hypotension).
Appropriate Use – Since sedation, fatigue, and lightheadedness are known effects of CBD hemp oil, particularly when consumed in large amounts, it is important that you do not use heavy machinery or attempt to drive while under the effects of this therapeutic oil.
Motor Functions – The sluggishness that many people associate with being “high” can be a side effect of concentrated CBD oil use, resulting in motor function impairment. This effect is temporary and passes in a matter of hours.
Weight Gain – Appetite stimulation, or at least regulation, is a side effect of CBD oil. So, if you are already struggling with obesity, be sure to monitor your intake of food to prevent overeating, snacking between meals and additional weight gain.
Oil Quality – The most dangerous aspect of CBD oil is potentially using low-quality oil or CBD oil that hasn’t been properly produced. With thousands of small businesses getting involved in the medicinal marijuana industry, it is more important than ever to research brands and pay attention to consumer reports concerning these oils.
Pregnancy – Research on the use of CBD oil during pregnancy is unfortunately lacking, but most experts do not recommend it. Other anecdotal reports support its use, particularly for aching muscles and anxiety or depression. Before using this oil – or any essential oil – while pregnant, always speak to a doctor about your particular condition.
SOURCE:
http://www.cbdoilcanadahq.ca/laws/
• Chronic pain and inflammation
• Arthritis
• Sleep disorders and insomnia
• Anxiety, stress, and depression
• Skin conditions
• Low appetite and poor metabolic function
• Weaker immune system
• Chronic diseases and cancer
Pain
CBD oil due to its analgesic properties is commonly recommended for chronic pain of all kinds, ranging from back pain to the full-body agony of cancer. It can disrupt the activity of pain receptors in the body and instead cause a release of neurotransmitters such as serotonin and dopamine – “feel good” compounds that can ease discomfort and pain, even if the pharmaceutical painkillers have no effect.
Nausea
CBD oil can cure vomiting and nausea. The non-psychotropic components of this oil activate certain autoreceptors, which causes antiemetic/anti-nausea effects in the body.
Inflammation
When it comes to inflammation, some people can only find relief with CBD oil, particularly those with advanced cases of rheumatoid arthritis, multiple sclerosis, migraines, joint disorders, and pervasive muscle pain. In some cases, people have reported nearly miraculous improvement in the inflammatory symptoms of chronic diseases.
Anxiety
CBD hemp oil is well known to reduce feelings of anxiety and stress, as well as prevent depressive episodes by increasing the levels of “positive” hormones and neurotransmitters in the body. Although some people claim that marijuana makes them “paranoid” or anxious, that is largely due to the psychotropic THC found in cannabis.
Alzheimer’s Disease
A number of studies have connected the use of cannabidiol (CBD) with decreased occurrence and severity of neurodegenerative diseases, such as Alzheimer’s and Huntington’s disease. This presents yet another exciting development for medical researchers, given the persistent challenges to finding effective solutions for these conditions.
Epilepsy
Highly concentrated doses of CBD oil have been successfully used to treat epilepsy in a number of research studies. While there has been quite a limited success in medication to prevent or treat epilepsy, the physical and neurological regulatory properties of CBD oil represent an exciting new solution for people with this seizure-inducing condition.
Cancer
Another major reason why CBD oil has been positively received in some parts of the medical community is its apparent effect on cancer and tumor growth. In multiple studies, the use of CBD oil (even direct injection into tumors) has resulted in tumor reduction or elimination. The antioxidants in CBD hemp oil also provide anti-mutagenic properties and lower users’ risk of cancer.
Anti-psychotic
Studies performed on animals and humans have found that CBD oil has anti-psychotic properties too. The research supports the idea that this oil could be a possible therapeutic option in treating psychosis such as schizophrenia.
Sleep
There is a strong sedative quality to CBD hemp oil, making it a popular remedy for people with insomnia, sleeplessness, interrupted sleep, post-traumatic stress disorder, restless leg disorder, and other night-time issues. Inhaling a small amount of CBD oil, applying it to your chest, or even putting a few drops on your pillow can help you get the good night’s sleep you’ve been seeking.
Immune System
The majority of cannabinoids have been proven to have positive effects on the body’s immune system, particularly CBD oil, as it can help regulate overactive immune systems. This means less susceptibility to allergens, and a possible application for autoimmune diseases, which are some of the most difficult-to-treat medical conditions.
Appetite
CBD oil is also known to control the appetite. This is largely due to the release of certain hormones in the body that control hunger and satiety. By optimizing the levels of these hormones based on the actual needs of your body, you can establish a healthy appetite, particularly following surgery, extended illness or injury.
Skin Care
Improving the appearance of the skin, especially reducing the signs and symptoms of acne and eczema, are the great benefits of regular CBD oil use. Topical application is quite popular for this, whether in a diluted or undiluted form, depending on the severity of the skin affliction. The powerful anti-inflammatory properties of the oil can also soothe redness, itchiness, and swollen areas of the skin.
Diabetes
Studies show that cannabidiol present in CBD oil can control diabetes and lower the level of insulin. Although a lot more research needs to be done in this area of study, initial studies have laid the foundation for the use of CBD oil to lower the risk of diabetics.
Promotes Heart Health
CBD oil is highly beneficial for the cardiovascular system too. It enhances the vasorelaxation of the arteries, protecting it against the vascular damage caused by inflammation in a high glucose environment. However, deeper studies need to be made in order to fully explore its dosage and effects on cardiovascular health.
Reduces Drug Relapses
The non-psychoactive constituent of Cannabis sativa, cannabidiol, has therapeutic uses in treating psychiatric disorders. It is used to fight alcoholism and cocaine addiction, which means it reduces alcohol and drug relapses.
Dosage
An appropriate dosage of CBD oil will depend on the individual, as well as the severity of the health condition a person is trying to remedy.
Chronic pain – 5 mg per day until the pain subsides.
Multiple sclerosis – Patients may take 80 mg per day for 2-3 weeks at a time to soothe their symptoms.
Medicinal applications – The average amount for most medicinal applications is 25 mg, taken twice per day.
If this is not sufficient for calming your symptoms, a gradual increase of another 25 mg per day, over the course of 3-4 weeks, is recommended. While there have been no reports of more serious side effects when this oil is taken in larger concentrations, it is best to slowly increase your dose to find a comfortable and effective level, given your individual characteristics and needs. [20]
Is CBD Oil Legal?
CBD oil is not legal everywhere. It is banned/restricted by countries such as UAE, Dubai, and Saudi Arabia. Although CBD oil is illegal in many of the US states too, some have legalized its use for medicinal purposes. While the number would be ever-changing, as of 2016 there are 17 states in the US which have legalized the use of low THC, high CBD products for medical reasons in limited situations. These states include Alabama, Georgia, Iowa, Kentucky, Florida, Mississippi, Louisiana, Missouri, North Carolina, Oklahoma, South Carolina, Wisconsin, Wyoming, Tennessee, Texas, Utah, and Virginia. It is advisable to consult your local health specialist before use.
Side Effects of CBD Oil
There are a number of possible side effects to using CBD oil, such as fatigue, dry mouth, lightheadedness, hypotension, and impaired motor functions. However, when used in moderate amounts, most people do not experience these side effects, and none of them are known for being fatal or particularly dangerous. [22] More than 20,000 studies have been done in the past 15 years on cannabis, hemp, and cannabinoids, and the results have been overwhelmingly supportive of the therapeutic potential and viability of CBD oil. That being said, some people should be cautious before using this powerful oil.
Blood Pressure – One of the notable soothing benefits of CBD oil is its effect on blood pressure, helping protect heart health and promote calmness in the body. However, if you are already taking medication for hypertension, combining this with CBD oil can potentially cause dangerously low blood pressure (hypotension).
Appropriate Use – Since sedation, fatigue, and lightheadedness are known effects of CBD hemp oil, particularly when consumed in large amounts, it is important that you do not use heavy machinery or attempt to drive while under the effects of this therapeutic oil.
Motor Functions – The sluggishness that many people associate with being “high” can be a side effect of concentrated CBD oil use, resulting in motor function impairment. This effect is temporary and passes in a matter of hours.
Weight Gain – Appetite stimulation, or at least regulation, is a side effect of CBD oil. So, if you are already struggling with obesity, be sure to monitor your intake of food to prevent overeating, snacking between meals and additional weight gain.
Oil Quality – The most dangerous aspect of CBD oil is potentially using low-quality oil or CBD oil that hasn’t been properly produced. With thousands of small businesses getting involved in the medicinal marijuana industry, it is more important than ever to research brands and pay attention to consumer reports concerning these oils.
Pregnancy – Research on the use of CBD oil during pregnancy is unfortunately lacking, but most experts do not recommend it. Other anecdotal reports support its use, particularly for aching muscles and anxiety or depression. Before using this oil – or any essential oil – while pregnant, always speak to a doctor about your particular condition.
SOURCE:
http://www.cbdoilcanadahq.ca/laws/
(4) Cannabichromene (CBC)
What is Cannabichromene?
Cannabichromene (CBC) is the second most abundant cannabinoid. Believe it or not, many strains contain higher levels of CBC than CBD. Why is it that so much attention has been put on researching CBD and not CBC? While it is true that CBD has many medicinal effects, much less research has been done on cannabichromene.
While little research has been done on Cannabichromene, it is one of the most prevalent cannabinoids in the marijuana plant. According to a study done by the federal government’s Marijuana Research Project in 1981, Cannabichromene is the second most abundant cannabinoid, after THC.
Why is it that nobody ever talks about Cannabichromene? Everyone acknowledges THC as the cannabinoid that gets you high, and many assume that CBD is the cannabinoid with all of the medical potential, but this viewpoint is too simplistic. In reality, all of the cannabinoids interact with each other in a complex manner, each with their own properties.
If we truly learn the difference between all of the cannabinoids, then we can start to understand that specific strains with different cannabinoid ratios will be better for different medical ailments. To start, it helps to know a bit about how the cannabinoids are synthesized in the plant.
Cannabichromene gets synthesized in a manner very similar to THC and CBD. CBGA is the precursor cannabinoid that eventually gets catalyzed to turn into THCA, CBDA, or CBCA. When exposed to heat, all of these cannabinoids get the “A” dropped, and the three cannabinoids THC, CBD, and CBC now will be present.
The boiling point of Cannabichromene is 428 degrees Fahrenheit (220 degrees Celsius). Anyone vaporizing who is looking to feel the effects of Cannabichromene should keep this in mind. Most vaporizers are a bit below this temperature, so people who vape would not get large amounts of Cannabichromene.
What are the effects of CBC?
While Cannabichromene is non-psychoactive, it does have medicinal properties of its own. It also interacts with THC in a synergistic manner, increasing the pain relieving effects of THC.
Cannabichromene is known to interact with many receptors. Many people know that the cannabinoids interact with the CB1 and CB2 receptors, but they also interact with others. Cannabichromene, in particular, is known to interact with the TRPV1 and TRPA1 receptors as well, which results in some of its medicinal properties.
It seems likely that cannabichromene is partially responsible for providing the high that so many have come to enjoy. Since pure THC can cause a lot of paranoia and anxiety, we see that many of the cannabinoids and terpenes tame this effect. Research has also shown that CBC specifically is a sedative, even though its mechanism of action still remains unknown. Also agreeing with this, another study found that mice tend to slow down when given CBC.
Cannabis has long been touted for its sedative properties. Cannabichromene could be one of the key contributing factors to this effect. Cannabis strains have a wide range of sedative effects. While most strains are at least somewhat relaxing, sativas can be known to provide a euphoric buzz of energy, while indicas typically give more of a sleepy effect. While terpenes such as myrcene and linalool are typically given credit for providing the sedative effects of a cannabis, it seems that many have overlooked the possibility of Cannabichromene also playing an important factor into the sedative nature of marijuana.
We find that the cannabis plant utilizes the entourage effect, which gets its potency from the combination of the cannabinoids and terpenes working together. Perhaps some users would prefer higher levels of Cannabichromene, while others would prefer more myrcene.
The entourage effect is great for many reasons. For example, one study found that THC impaired male reproductive behavior in mice, but this did not occur when Cannabichromene was present. As we see, Cannabichromene is yet another cannabinoid that takes away some of the negative aspects of THC.
Unfortunately, since there is a lack of knowledge of CBC, there are not any strains that are touted for having a high CBC content. While some labs do test for CBC levels, many do not and it still remains difficult to know how much CBC is contained in each strain.
Medical Uses of CBC
One of the first major studies focusing on CBC found that CBC has many medicinal benefits. To start, Prof. ElSohly found that CBC has better anti-inflammatory properties than typical medication. His group also discovered that cannabichromene had strong antibacterial properties and was even effective against E. coli. The study found that CBC also has mild to moderate antifungal activity against black mold.
Cannabichromene, in addition to having anti-fungal properties, has also been proven effective against E.Coli One study in 2010 found that THC, CBC, and CBD has anti-depressant properties in rats. It was found that roughly 10 times less CBC was needed to have the same effect as CBD, implying that CBC may help significantly with elevating one’s mood. CBC’s method of activation remains unknown.
A study in the same year looked to compare the effectiveness of THC and CBC for their anti-inflammatory properties. They found that CBC had anti-emetic properties, or can reduce swelling. While THC does have these effects as well, they did not occur when the CB2 receptor is blocked. CBC, on the other hand, reduced swelling even when the CB1 and CB2 receptors were blocked. This shows how CBC had pharmacological activity besides interacting with the CB1 and CB2 receptors. When THC and CBC were used in tandem, the anti-swelling properties got even better.
In 2012, another animal model study suggested that CBC has anti-inflammatory properties throughout the intestines. The anti-inflammatory properties of CBC seemed to not be related to the CB1, CB2, or TRPA1 receptors. The mystery continues, as we still do not understand the mechanism for how CBC has these effects. It is thought that these anti-inflammatory properties will help with arthritis and cardiovascular disease. CBC also is less toxic than other anti-inflammatory medications, which suggests that CBC would be safer at higher doses.
While much is still unknown about CBC, the limited research shows potential for anti-inflammatory, anti-bacterial, and anti-cancer effects.
CBC and CBD have painkilling effects, which seems to be mediated by the CB1 and TRPA1 receptors. While it is great to know that CBC has analgesic properties for rats, ultimately more studies are needed with humans.
CBC Neurogenesis
Cannabichromene could be responsible for helping new neurons grow (neurogenesis).
Cannabichromene has also been found to help stimulate the growth of brain cells. They noticed that CBC interacted with the adenosine A1 receptor to promote these effects, demonstrating that CBC interacts in yet another unique way. While many drugs such as opiates, alcohol, nicotine, and cocaine can impair brain cells, it seems that marijuana has the potential to do the opposite.
Cannabichromene is also useful for treating migraines. It also inhibits the uptake of anandamide, the endocannabinoid naturally occurring in our brain, thus allowing for anandamide to stay in the bloodstream longer. This may contribute to some of Cannabichromene’s anti-cancer properties, since anandamide has been shown to inhibit breast cancer cell growth.
Patients with glaucoma should be advised that THC does help with eye pressure, but it appears that Cannabichromene has no such effects.
As research continues, we will learn more about the potential benefits of Cannabichromene and have a better understanding on how to make proper medication out of this unique cannabinoid.
SOURCE:
https://learn.woahstork.com/cannabinoids/cbc/
Cannabichromene (CBC) is the second most abundant cannabinoid. Believe it or not, many strains contain higher levels of CBC than CBD. Why is it that so much attention has been put on researching CBD and not CBC? While it is true that CBD has many medicinal effects, much less research has been done on cannabichromene.
While little research has been done on Cannabichromene, it is one of the most prevalent cannabinoids in the marijuana plant. According to a study done by the federal government’s Marijuana Research Project in 1981, Cannabichromene is the second most abundant cannabinoid, after THC.
Why is it that nobody ever talks about Cannabichromene? Everyone acknowledges THC as the cannabinoid that gets you high, and many assume that CBD is the cannabinoid with all of the medical potential, but this viewpoint is too simplistic. In reality, all of the cannabinoids interact with each other in a complex manner, each with their own properties.
If we truly learn the difference between all of the cannabinoids, then we can start to understand that specific strains with different cannabinoid ratios will be better for different medical ailments. To start, it helps to know a bit about how the cannabinoids are synthesized in the plant.
Cannabichromene gets synthesized in a manner very similar to THC and CBD. CBGA is the precursor cannabinoid that eventually gets catalyzed to turn into THCA, CBDA, or CBCA. When exposed to heat, all of these cannabinoids get the “A” dropped, and the three cannabinoids THC, CBD, and CBC now will be present.
The boiling point of Cannabichromene is 428 degrees Fahrenheit (220 degrees Celsius). Anyone vaporizing who is looking to feel the effects of Cannabichromene should keep this in mind. Most vaporizers are a bit below this temperature, so people who vape would not get large amounts of Cannabichromene.
What are the effects of CBC?
While Cannabichromene is non-psychoactive, it does have medicinal properties of its own. It also interacts with THC in a synergistic manner, increasing the pain relieving effects of THC.
Cannabichromene is known to interact with many receptors. Many people know that the cannabinoids interact with the CB1 and CB2 receptors, but they also interact with others. Cannabichromene, in particular, is known to interact with the TRPV1 and TRPA1 receptors as well, which results in some of its medicinal properties.
It seems likely that cannabichromene is partially responsible for providing the high that so many have come to enjoy. Since pure THC can cause a lot of paranoia and anxiety, we see that many of the cannabinoids and terpenes tame this effect. Research has also shown that CBC specifically is a sedative, even though its mechanism of action still remains unknown. Also agreeing with this, another study found that mice tend to slow down when given CBC.
Cannabis has long been touted for its sedative properties. Cannabichromene could be one of the key contributing factors to this effect. Cannabis strains have a wide range of sedative effects. While most strains are at least somewhat relaxing, sativas can be known to provide a euphoric buzz of energy, while indicas typically give more of a sleepy effect. While terpenes such as myrcene and linalool are typically given credit for providing the sedative effects of a cannabis, it seems that many have overlooked the possibility of Cannabichromene also playing an important factor into the sedative nature of marijuana.
We find that the cannabis plant utilizes the entourage effect, which gets its potency from the combination of the cannabinoids and terpenes working together. Perhaps some users would prefer higher levels of Cannabichromene, while others would prefer more myrcene.
The entourage effect is great for many reasons. For example, one study found that THC impaired male reproductive behavior in mice, but this did not occur when Cannabichromene was present. As we see, Cannabichromene is yet another cannabinoid that takes away some of the negative aspects of THC.
Unfortunately, since there is a lack of knowledge of CBC, there are not any strains that are touted for having a high CBC content. While some labs do test for CBC levels, many do not and it still remains difficult to know how much CBC is contained in each strain.
Medical Uses of CBC
One of the first major studies focusing on CBC found that CBC has many medicinal benefits. To start, Prof. ElSohly found that CBC has better anti-inflammatory properties than typical medication. His group also discovered that cannabichromene had strong antibacterial properties and was even effective against E. coli. The study found that CBC also has mild to moderate antifungal activity against black mold.
Cannabichromene, in addition to having anti-fungal properties, has also been proven effective against E.Coli One study in 2010 found that THC, CBC, and CBD has anti-depressant properties in rats. It was found that roughly 10 times less CBC was needed to have the same effect as CBD, implying that CBC may help significantly with elevating one’s mood. CBC’s method of activation remains unknown.
A study in the same year looked to compare the effectiveness of THC and CBC for their anti-inflammatory properties. They found that CBC had anti-emetic properties, or can reduce swelling. While THC does have these effects as well, they did not occur when the CB2 receptor is blocked. CBC, on the other hand, reduced swelling even when the CB1 and CB2 receptors were blocked. This shows how CBC had pharmacological activity besides interacting with the CB1 and CB2 receptors. When THC and CBC were used in tandem, the anti-swelling properties got even better.
In 2012, another animal model study suggested that CBC has anti-inflammatory properties throughout the intestines. The anti-inflammatory properties of CBC seemed to not be related to the CB1, CB2, or TRPA1 receptors. The mystery continues, as we still do not understand the mechanism for how CBC has these effects. It is thought that these anti-inflammatory properties will help with arthritis and cardiovascular disease. CBC also is less toxic than other anti-inflammatory medications, which suggests that CBC would be safer at higher doses.
While much is still unknown about CBC, the limited research shows potential for anti-inflammatory, anti-bacterial, and anti-cancer effects.
CBC and CBD have painkilling effects, which seems to be mediated by the CB1 and TRPA1 receptors. While it is great to know that CBC has analgesic properties for rats, ultimately more studies are needed with humans.
CBC Neurogenesis
Cannabichromene could be responsible for helping new neurons grow (neurogenesis).
Cannabichromene has also been found to help stimulate the growth of brain cells. They noticed that CBC interacted with the adenosine A1 receptor to promote these effects, demonstrating that CBC interacts in yet another unique way. While many drugs such as opiates, alcohol, nicotine, and cocaine can impair brain cells, it seems that marijuana has the potential to do the opposite.
Cannabichromene is also useful for treating migraines. It also inhibits the uptake of anandamide, the endocannabinoid naturally occurring in our brain, thus allowing for anandamide to stay in the bloodstream longer. This may contribute to some of Cannabichromene’s anti-cancer properties, since anandamide has been shown to inhibit breast cancer cell growth.
Patients with glaucoma should be advised that THC does help with eye pressure, but it appears that Cannabichromene has no such effects.
As research continues, we will learn more about the potential benefits of Cannabichromene and have a better understanding on how to make proper medication out of this unique cannabinoid.
SOURCE:
https://learn.woahstork.com/cannabinoids/cbc/
What are Terpenes?
(5) What are Terpenes?
(6) Terpenes: The Most Common Language in the World
Terpenes are some of the most powerful synergistic compounds found in hemp. Terpenes greatly influence the effects of the unique cannabinoids found in hemp and they play a key role in the way you feel.
Terpenes are not unique to hemp. They are found in many other plants. Hemp is unique in the vast amount and diversity of terpenes present within a single plant.
Most industrial hemp is characterized by its tall stalks. It is grown for its fibers, which are the strongest plant fibers in nature. Industrial hemp is also grown for its seed which contain essential amino acids but no phytocannabinoids.
This type of industrial hemp contains very few phytocannabinoids and limited amounts of other synergistic compounds.
Industrial hemp is defined by the US Government in section 7606 of the 2014 Federal Farm Bill as ANY Cannabis Sativa L. that produces naturally less than 0.3% THC on a dry weight basis.
Industrial hemp is defined by the US Government in section 7606 of the 2014 Federal Farm Bill as ANY Cannabis Sativa L. that produces naturally less than 0.3% THC on a dry weight basis.
The videos below are independent, third party videos that are publicly available on YouTube. The creators of those videos have not endorsed a specific brand of hemp oil. The videos are presented here to enable you to learn more in order to make an informed decision. Please watch the videos below...
(7) Why You Need CBD:
(8) CBD is Great for Anxiety - Dr.Hicks
(9) Your Endocannabinoid System Explained:
(10) Doctors Speak Out On The Benefits of CBD:
(11) How Hemp Threatens The Corporatocracy:
(12) Visualization of the endocannabinoid signaling system:
(13) The Most Powerful Plant on Earth?
(14) Cannabinoid System in Neuroprotection
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